Bibliothèque

Safety and Efficacy of Conversion Therapy After Systemic Chemotherapy in Advanced Esophageal Cancer with Distant Metastases: A Multicenter Retrospective Observational Study.

BACKGROUND: Patients with esophageal squamous cell carcinoma (ESCC) with distant metastasis were treated with systemic chemotherapy. Recent advances in multimodal treatments have made conversion thera…

Thérapies de Conversion

Tsuji, T., Matsuda, S., Sato, Y., Tanaka, K., Sasaki, K., Watanabe, M., Hamai, Y., Nasu, M., Saze, Z., Nakashima, Y., Nomura, M., Yamamoto, S., Booka, E., Ishiyama, K., Bamba, T., Sakanaka, K., Tsushima, T., Takeuchi, H., Kato, K., & Kawakubo, H. (2025). Safety and Efficacy of Conversion Therapy After Systemic Chemotherapy in Advanced Esophageal Cancer with Distant Metastases: A Multicenter Retrospective Observational Study.. Ann Surg Oncol, 32(1), 274-283. https://doi.org/10.1245/s10434-024-16196-7

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Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.

BACKGROUND: Immune checkpoint inhibitors (ICIs) have demonstrated efficacy in the treatment of resectable and advanced gastric cancer. However, their effectiveness in initially unresectable gastric ca…

Thérapies de Conversion

Li, S., Xu, Q., Yu, W., Liu, Z., Cui, X., Wei, M., Shi, D., Zhao, W., Song, X., Zhang, D., Nan, Z., Chu, J., Wang, S., Nie, S., Dai, X., & Liu, L. (2025). Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.. Front Immunol, 16, 1753749. https://doi.org/10.3389/fimmu.2025.1753749

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"Praying in or preying on my skin": a narrative study of transgender and gender non-conforming individuals' experiences with religion and gender identity in India.

This narrative analysis paper explores how gender non-conforming individuals interact with faith across Indian religious traditions. Drawing upon four in-depth semi-structured interviews with the part…

Neurosciences des Croyances Thérapies de Conversion

Ashok, S., & Saranya, T. S. (2025). "Praying in or preying on my skin": a narrative study of transgender and gender non-conforming individuals' experiences with religion and gender identity in India.. Front Sociol, 10, 1642404. https://doi.org/10.3389/fsoc.2025.1642404

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Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma.

Advanced hepatocellular carcinoma (HCC) has a poor prognosis. Conversion therapy based on non-surgical local therapy and drug therapy is an effective treatment for unresectable HCC. We report a case o…

Thérapies de Conversion

Mao, J., Zhang, H., Yang, X., Yao, Y., Sun, X., & Yan, Q. (2025). Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma.. Front Oncol, 15, 1627281. https://doi.org/10.3389/fonc.2025.1627281

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Pathologic complete response of advanced hepatoid adenocarcinoma of the stomach following immuno-chemotherapy and conversion surgery: a rare case report and review of the literature.

BACKGROUND: Hepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer (GC) characterized by alpha-fetoprotein (AFP) production and invasive liver and lymph node metastases, typi…

Thérapies de Conversion

Li, Y., Wang, Y., Yu, T., Wang, D., Ma, H., Ma, J., & Da, M. (2025). Pathologic complete response of advanced hepatoid adenocarcinoma of the stomach following immuno-chemotherapy and conversion surgery: a rare case report and review of the literature.. Front Oncol, 15, 1648766. https://doi.org/10.3389/fonc.2025.1648766

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TPF regimen improves conversion surgery and short-term survival in patients with locally unresectable advanced gastric cancer.

OBJECTIVE: To compare the efficacy and safety of TPF versus FOLFOX regimens in conversion therapy for locally unresectable advanced gastric cancer (LAUGC) and to identify prognostic factors influencin…

Thérapies de Conversion

Duan, T., Ma, D., Bai, Z., Ding, X., & Zhang, X. (2025). TPF regimen improves conversion surgery and short-term survival in patients with locally unresectable advanced gastric cancer.. Am J Transl Res, 17(8), 6068-6079. https://doi.org/10.62347/FFQN8329

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Development and validation of a prognostic nomogram for unresectable pancreatic ductal adenocarcinoma with synchronous liver metastases: a study based on the SEER database and an external cohort.

BACKGROUND: Pancreatic ductal adenocarcinoma with synchronous liver metastases (PDACLM) represents a highly aggressive malignancy with limited treatment options and poor prognosis. While conversion th…

Thérapies de Conversion

Huan, L., He, Q., Cao, Y., Liu, C., & Li, Y. (2025). Development and validation of a prognostic nomogram for unresectable pancreatic ductal adenocarcinoma with synchronous liver metastases: a study based on the SEER database and an external cohort.. Front Oncol, 15, 1636715. https://doi.org/10.3389/fonc.2025.1636715

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Additions of trastuzumab to preoperative chemotherapy or chemoimmunotherapy for patients with potentially resectable stage III to IV HER2-positive gastric cancer.

BACKGROUND: Whether the addition of trastuzumab to chemo(immuno)therapy for the preoperative treatment of patients with potentially resectable HER2-positive gastric cancer has clinical benefits remain…

Thérapies de Conversion

Zhang, X., Tian, Y., Wang, H., Song, S., Chen, Y., Liu, N., Zhang, C., Huang, X., Jiang, H., & Hou, H. (2025). Additions of trastuzumab to preoperative chemotherapy or chemoimmunotherapy for patients with potentially resectable stage III to IV HER2-positive gastric cancer.. Front Immunol, 16, 1624943. https://doi.org/10.3389/fimmu.2025.1624943

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Postoperative hepatitis B virus reactivation and its impact on survival in HBV-related hepatocellular carcinoma patients undergoing conversion therapy with interventional therapy combined with tyrosine kinase inhibitors and immune checkpoint inhibitors.

OBJECTIVE: This study aimed to investigate hepatitis B virus (HBV) reactivation and its impact on postoperative survival in patients with HBV-related hepatocellular carcinoma (HCC) who underwent conve…

Thérapies de Conversion

Xu, S., Pang, Q., Wei, M., Liu, D., Yuan, D., Bai, T., Wang, X., Tang, Z., & Wu, F. (2025). Postoperative hepatitis B virus reactivation and its impact on survival in HBV-related hepatocellular carcinoma patients undergoing conversion therapy with interventional therapy combined with tyrosine kinase inhibitors and immune checkpoint inhibitors.. Front Cell Infect Microbiol, 15, 1598193. https://doi.org/10.3389/fcimb.2025.1598193

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Local-region treatment comparison following conversion therapy of hepatocellular carcinoma: a period and age-dependent analysis.

BACKGROUND: Transarterial chemoembolization (TACE) is a potential conversion therapeutic strategy for unresectable hepatocellular carcinoma (uHCC). However, therapeutic options following conversion th…

Thérapies de Conversion

Hu, J., Zhao, S., Zuo, M., Li, C. H., Yao, W., Yang, X., Xing, W., & Song, P. (2025). Local-region treatment comparison following conversion therapy of hepatocellular carcinoma: a period and age-dependent analysis.. Ther Adv Med Oncol, 17, 17588359251316665. https://doi.org/10.1177/17588359251316665

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Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.

BACKGROUND: Although immune checkpoint inhibitors (ICIs) and anti-angiogenic drugs have demonstrated effectiveness in treating advanced gastric cancer (GC), their role in neoadjuvant or conversion the…

Thérapies de Conversion

Zhan, Z., Chen, B., Xu, S., Lin, R., Chen, H., Ma, X., Lin, X., Huang, W., Zhuo, C., Chen, Y., & Guo, Z. (2025). Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.. Front Immunol, 16, 1518217. https://doi.org/10.3389/fimmu.2025.1518217

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Recognizing the Role for Conversion Therapy in Metastatic Esophageal Squamous Cell Cancer (ESCC): A Call for Future Study.

Thérapies de Conversion

Baskin, A. S., & Velotta, J. B. (2025). Recognizing the Role for Conversion Therapy in Metastatic Esophageal Squamous Cell Cancer (ESCC): A Call for Future Study.. Ann Surg Oncol, 32(1), 24-26. https://doi.org/10.1245/s10434-024-16335-0

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