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Integrative multi-omics analysis reveal novel therapeutic targets for glioblastoma.

BACKGROUND AND OBJECTIVES: Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults, yet effective therapeutic strategies remain limited. A comprehensive exploratio…

Neurosciences des Croyances

Li, J., Yuan, Y., He, Y., Wang, Z., Chen, S., Li, W., Ren, H., Ou, Y., Zeng, Y., Yang, W., & Liu, Y. (2025). Integrative multi-omics analysis reveal novel therapeutic targets for glioblastoma.. Int J Surg, 111(11), 8159-8168. https://doi.org/10.1097/JS9.0000000000002941

01/11/2025 Lire →

Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer's dementia.

The biology of individual lipid species and their relevance in Alzheimer's disease (AD) remains incompletely understood. To explore the lipidomic biomarkers associated with cognition function and neur…

Neurosciences des Croyances

Chen, C. Y., Maner-Smith, K., Khadka, M., Ahn, J., Gulbin, X. L., Ivanova, A. A., Dammer, E. B., Seyfried, N. T., Bennett, D. A., Hajjar, I. M., & Ortlund, E. A. (2025). Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer's dementia.. Nat Commun, 16(1), 9627. https://doi.org/10.1038/s41467-025-64328-8

31/10/2025 Lire →

Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer's disease.

Age and the ε4 variant of the apolipoprotein E gene (APOE ε4) are two major drivers of Alzheimer's disease (AD). APOE is also the major determinant of longevity. How age and APOE interact in the devel…

Neurosciences des Croyances

Amin, N., Liu, J., Sproviero, W., Arnold, M., Batra, R., Bonnechere, B., Chiou, Y. J., Fernandes, M., Krumsiek, J., Newby, D., Nho, K., Kim, J. P., Saykin, A. J., Shi, L., Winchester, L. M., Yang, Y., Nevado-Holgado, A. J., Kastenmüller, G., Kaddurah-Daouk, R., & van, D. u. i. j. n. . C. M. (2025). Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer's disease.. Transl Psychiatry, 15(1), 460. https://doi.org/10.1038/s41398-025-03625-8

31/10/2025 Lire →

A tale of two lineages: comparative biogeography across the Southern Cone of two South American Carex (Cyperaceae) groups.

BACKGROUND AND AIMS: The Carex phalaroides group and Carex sect. Bracteosellae are two species complexes that exhibit similar distribution patterns, despite being two evolutionary independent lineages…

Neurosciences des Croyances

Morales-Alonso, A., Muñoz, S. c. h. �. �. l. e. r. . P., Villaverde, T., & Jiménez-Mejías, P. (2025). A tale of two lineages: comparative biogeography across the Southern Cone of two South American Carex (Cyperaceae) groups.. Ann Bot. https://doi.org/10.1093/aob/mcaf262

22/10/2025 Lire →

Beyond the Genotype: A Multi-Omic Analysis of APOEe4's Role in Alzheimer's Disease.

Alzheimer's disease (AD) is characterized by widespread molecular dysregulation, with the APOEe4 allele recognized as its strongest genetic risk factor. However, the mechanisms by which APOEe4 drives …

Neurosciences des Croyances

Markov, Y., Priyanka, A., Xu, L., Wang, W., Thrush-Evensen, K., Gonzalez, J., Borrus, D., Kasamoto, J., Sehgal, R., Zou, G., Fraij, J., Carlyle, B. C., Horvath, S., Bennett, D. A., Zhao, H., van, D. y. c. k. . C. H., Lam, T. T., Levine, M. E., & Higgins-Chen, A. T. (2025). Beyond the Genotype: A Multi-Omic Analysis of APOEe4's Role in Alzheimer's Disease.. bioRxiv. https://doi.org/10.1101/2025.10.16.682426

16/10/2025 Lire →

Comparative chloroplast genomics of Erigeron (Asteroideae, Asteraceae).

The genus Erigeron L. (Astereae, Asteroideae, Asteraceae), commonly known as fleabanes, comprises approximately 457 species with a near-cosmopolitan distribution. However, taxonomic discrepancies pers…

Neurosciences des Croyances

Abdullah, Rahmatulla, A., Chen, C., Yan, R., Naz, I., Heidari, P., Ahmed, I., Vallada, A., & Tian, X. (2025). Comparative chloroplast genomics of Erigeron (Asteroideae, Asteraceae).. BMC Plant Biol, 25(1), 1356. https://doi.org/10.1186/s12870-025-07484-9

10/10/2025 Lire →

Comparative chloroplast genomes of Sophora species: identification of variable DNA markers and phylogenetic relationships within the genus.

BACKGROUD: Sophora L. is a medicinally significant genus within Papilionoideae (Fabaceae), renowned for its medicinal, ecological, and economic importance. However, taxonomic and phylogenetic uncertai…

Neurosciences des Croyances

Duan, N., Ru, D., & Liu, B. (2025). Comparative chloroplast genomes of Sophora species: identification of variable DNA markers and phylogenetic relationships within the genus.. BMC Plant Biol, 25(1), 1308. https://doi.org/10.1186/s12870-025-07398-6

03/10/2025 Lire →

Nationwide evaluation of readability, quality, and cultural sensitivity of online brain cancer education materials in the United States.

BACKGROUND: Patients with primary brain tumors navigate a devastating diagnosis and cognitive and physical decline. Available educational materials should be easily comprehensible, informative, reliab…

Neurosciences des Croyances

Nilak, J., Spadt, L., & Cohen, A. L. (2025). Nationwide evaluation of readability, quality, and cultural sensitivity of online brain cancer education materials in the United States.. Neurooncol Pract, 12(5), 901-911. https://doi.org/10.1093/nop/npaf035

01/10/2025 Lire →

Cumulative social advantage is associated with slower epigenetic aging and lower systemic inflammation.

BACKGROUND: Social relationships are established determinants of health across the lifespan, yet the cumulative and multidimensional effects of sustained social advantage on biological aging remain po…

Neurosciences des Croyances

Ong, A. D., Mann, F. D., & Kubzansky, L. D. (2025). Cumulative social advantage is associated with slower epigenetic aging and lower systemic inflammation.. Brain Behav Immun Health, 48, 101096. https://doi.org/10.1016/j.bbih.2025.101096

01/10/2025 Lire →

How golden age Arab-Islamic scholars revolutionized sleep physiology and dream analysis.

Medieval Arab-Islamic scholars (7th-13th centuries CE) made pivotal but underacknowledged contributions to sleep science, blending empirical observation with theological insight. This review examines …

Neurosciences des Croyances

BaHammam, A. S. (2025). How golden age Arab-Islamic scholars revolutionized sleep physiology and dream analysis.. J Taibah Univ Med Sci, 20(5), 596-611. https://doi.org/10.1016/j.jtumed.2025.07.013

01/10/2025 Lire →

Religious and spiritual experiences from a neuroscientific and complex systems perspective.

The emergence of spiritual and religious practices can be seen as a major cognitive transition in the evolution of biological organisms. Spiritual and religious experiences are closely linked to evolv…

Neurosciences des Croyances

Jedlicka, P., & Havenith, M. N. (2025). Religious and spiritual experiences from a neuroscientific and complex systems perspective.. Neurosci Biobehav Rev, 177, 106319. https://doi.org/10.1016/j.neubiorev.2025.106319

01/10/2025 Lire →

Rapid loss of consciousness in cattle following nonstun slaughter: evidence from a systematic review.

BACKGROUND: Accepting that it is ethical for meat to be consumed as food, then, in any context, religious or secular, it is indefensible for animals to be subjected to undue pain. Animal slaughter mus…

Neurosciences des Croyances

Hascalovici, J. R., Schipper, H. M., Regenstein, J. M., Rosen, S. D., Zivotofsky, A., St-Jean, G., Freilich, S., Morrison, T. J., Rabkin, S. W., & Haut, S. (2025). Rapid loss of consciousness in cattle following nonstun slaughter: evidence from a systematic review.. Am J Vet Res, 86(10). https://doi.org/10.2460/ajvr.25.02.0049

01/10/2025 Lire →